Preparation and structural characterization of a new class of stable thioetones: ortho-hydroxythioacetophenones
Trung Thanh Nguyen, Thach Ngoc Le, Poul Erik Hansen and Fritz Duus
Tetrahedron Letters 47 (2006) 8433–8435
Abstract: Ortho-hydroxythioacetophenone and four structurally related ortho-hydroxyaryl methyl thioketones have been prepared from the corresponding ketones by reaction with gaseous H2S and HCl in ethanol under strictly controlled reaction conditions. The remarkable stability of the new monomeric thioketones seems to be due to a strong intramolecular O-H…S=C hydrogen bonding.